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Development of a versatile HPLC-based method to evaluate the activation status of small GTPases

Small GTPases cycle between an inactive GDP-bound and an active GTP-bound state to control various cellular events, such as cell proliferation, cytoskeleton organization, and membrane trafficking. Clarifying the guanine nucleotide-bound states of small GTPases is vital for understanding the regulati...

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Detalles Bibliográficos
Autores principales:	Araki, Makoto, Yoshimoto, Kaho, Ohta, Meguri, Katada, Toshiaki, Kontani, Kenji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668980/ https://www.ncbi.nlm.nih.gov/pubmed/34801548 http://dx.doi.org/10.1016/j.jbc.2021.101428

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