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Ischemic fasciitis conversion to myxofibrosarcoma: A case report

INTRODUCTION: Ischemic fasciitis is a rare pseudosarcomatous fibroblastic lesion. It is considered benign and generally occurs in the elderly. Long-term follow-up is rare therefore; the natural history is largely unknown. It is excised without specific attention to margins. CASE PRESENTATION: We pre...

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Detalles Bibliográficos
Autores principales: Lopez, Janelle, Rayhrer, Constanze Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668985/
https://www.ncbi.nlm.nih.gov/pubmed/34896963
http://dx.doi.org/10.1016/j.ijscr.2021.106664
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author Lopez, Janelle
Rayhrer, Constanze Sabine
author_facet Lopez, Janelle
Rayhrer, Constanze Sabine
author_sort Lopez, Janelle
collection PubMed
description INTRODUCTION: Ischemic fasciitis is a rare pseudosarcomatous fibroblastic lesion. It is considered benign and generally occurs in the elderly. Long-term follow-up is rare therefore; the natural history is largely unknown. It is excised without specific attention to margins. CASE PRESENTATION: We present a case of a 94-year-old female with ischemic fasciitis on the shoulder for which we have three years of follow-up. During this time, multiple re- excisions for recurrence were required. This lesion eventually progressed to myxofibrosarcoma. CLINICAL DISCUSSION: We suggest ischemic fasciitis may be a precursor to malignancy. Ischemic fasciitis itself is noted to have features similar to sarcoma on histopathology. Simple excision of ischemic fasciitis without margins may be inadequate therapy. CONCLUSION: Ischemic fasciitis or pseudosarcomatous fibroblastic lesion and myxofibrosarcoma have many histological similarities. A pseudosarcomatous fibroblastic lesion may be a precursor to myxofibrosarcoma and we recommend complete excision with negative margins at the initial treatment to prevent a recurrence.
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spelling pubmed-86689852021-12-15 Ischemic fasciitis conversion to myxofibrosarcoma: A case report Lopez, Janelle Rayhrer, Constanze Sabine Int J Surg Case Rep Case Report INTRODUCTION: Ischemic fasciitis is a rare pseudosarcomatous fibroblastic lesion. It is considered benign and generally occurs in the elderly. Long-term follow-up is rare therefore; the natural history is largely unknown. It is excised without specific attention to margins. CASE PRESENTATION: We present a case of a 94-year-old female with ischemic fasciitis on the shoulder for which we have three years of follow-up. During this time, multiple re- excisions for recurrence were required. This lesion eventually progressed to myxofibrosarcoma. CLINICAL DISCUSSION: We suggest ischemic fasciitis may be a precursor to malignancy. Ischemic fasciitis itself is noted to have features similar to sarcoma on histopathology. Simple excision of ischemic fasciitis without margins may be inadequate therapy. CONCLUSION: Ischemic fasciitis or pseudosarcomatous fibroblastic lesion and myxofibrosarcoma have many histological similarities. A pseudosarcomatous fibroblastic lesion may be a precursor to myxofibrosarcoma and we recommend complete excision with negative margins at the initial treatment to prevent a recurrence. Elsevier 2021-12-06 /pmc/articles/PMC8668985/ /pubmed/34896963 http://dx.doi.org/10.1016/j.ijscr.2021.106664 Text en © 2021 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Lopez, Janelle
Rayhrer, Constanze Sabine
Ischemic fasciitis conversion to myxofibrosarcoma: A case report
title Ischemic fasciitis conversion to myxofibrosarcoma: A case report
title_full Ischemic fasciitis conversion to myxofibrosarcoma: A case report
title_fullStr Ischemic fasciitis conversion to myxofibrosarcoma: A case report
title_full_unstemmed Ischemic fasciitis conversion to myxofibrosarcoma: A case report
title_short Ischemic fasciitis conversion to myxofibrosarcoma: A case report
title_sort ischemic fasciitis conversion to myxofibrosarcoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8668985/
https://www.ncbi.nlm.nih.gov/pubmed/34896963
http://dx.doi.org/10.1016/j.ijscr.2021.106664
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