Cargando…

Using a convolutional neural network for classification of squamous and non-squamous non-small cell lung cancer based on diagnostic histopathology HES images

Histological stratification in metastatic non-small cell lung cancer (NSCLC) is essential to properly guide therapy. Morphological evaluation remains the basis for subtyping and is completed by additional immunohistochemistry labelling to confirm the diagnosis, which delays molecular analysis and ut...

Descripción completa

Detalles Bibliográficos
Autores principales:	Le Page, Anne Laure, Ballot, Elise, Truntzer, Caroline, Derangère, Valentin, Ilie, Alis, Rageot, David, Bibeau, Frederic, Ghiringhelli, Francois
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669012/ https://www.ncbi.nlm.nih.gov/pubmed/34903781 http://dx.doi.org/10.1038/s41598-021-03206-x

Ejemplares similares

Prognostic value of Thyroid Transcription Factor-1 expression in lung adenocarcinoma in patients treated with anti PD-1/PD-L1
por: Galland, Loïck, et al.
Publicado: (2021)

Follicular helper-T cells restore CD8(+)-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy
por: Niogret, Julie, et al.
Publicado: (2021)

Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers
por: Ballot, Elise, et al.
Publicado: (2022)

Tumor Infiltrating Lymphocytes Signature as a New Pan-Cancer Predictive Biomarker of Anti PD-1/PD-L1 Efficacy
por: Ballot, Elise, et al.
Publicado: (2020)

PIK3CA and PIK3R1 tumor mutational landscape in a pan-cancer patient cohort and its association with pathway activation and treatment efficacy
por: Tharin, Zoé, et al.
Publicado: (2023)

Efficacy of platinum-based chemotherapy in metastatic breast cancer and HRD biomarkers: utility of exome sequencing
por: Galland, Loïck, et al.
Publicado: (2022)

Evaluation of tumor immune contexture among intrinsic molecular subtypes helps to predict outcome in early breast cancer
por: Klopfenstein, Quentin, et al.
Publicado: (2021)

Heat shock and HSP70 regulate 5-FU-mediated caspase-1 activation in myeloid-derived suppressor cells and tumor growth in mice
por: Pilot, Thomas, et al.
Publicado: (2020)

GTN Enhances Antitumor Effects of Doxorubicin in TNBC by Targeting the Immunosuppressive Activity of PMN-MDSC
por: Mabrouk, Nesrine, et al.
Publicado: (2023)

Exome-Based Genomic Markers Could Improve Prediction of Checkpoint Inhibitor Efficacy Independently of Tumor Type
por: Dalens, Lorraine, et al.
Publicado: (2023)

Induction of pyroptosis in colon cancer cells by LXRβ
por: Rébé, Cédric, et al.
Publicado: (2015)

Cell lines and immune classification of glioblastoma define patient’s prognosis
por: Klopfenstein, Quentin, et al.
Publicado: (2019)

Squamous intraepithelial lesions of the anal squamocolumnar junction: Histopathological classification and HPV genotyping
por: Clavero, Omar, et al.
Publicado: (2016)

RAS status and neoadjuvant chemotherapy impact CD8+ cells and tumor HLA class I expression in liver metastatic colorectal cancer
por: Ledys, Fanny, et al.
Publicado: (2018)

Splenic Volume as a Surrogate Marker of Immune Checkpoint Inhibitor Efficacy in Metastatic Non Small Cell Lung Cancer
por: Galland, Loïck, et al.
Publicado: (2021)

Immunoscore immune checkpoint using spatial quantitative analysis of CD8 and PD-L1 markers is predictive of the efficacy of anti- PD1/PD-L1 immunotherapy in non-small cell lung cancer
por: Ghiringhelli, François, et al.
Publicado: (2023)

HES1 and HES4 have non-redundant roles downstream of Notch during early human T-cell development
por: De Decker, Matthias, et al.
Publicado: (2020)

Automatic Detection of Oral Squamous Cell Carcinoma from Histopathological Images of Oral Mucosa Using Deep Convolutional Neural Network
por: Das, Madhusmita, et al.
Publicado: (2023)

TCR Clonality and Genomic Instability Signatures as Prognostic Biomarkers in High Grade Serous Ovarian Cancer
por: Lecuelle, Julie, et al.
Publicado: (2021)

Histopathological classification of non-functioning pituitary neuroendocrine tumors
por: Manojlovic-Gacic, Emilija, et al.
Publicado: (2017)

Leveraging Attention-Based Convolutional Neural Networks for Meningioma Classification in Computational Histopathology
por: Sehring, Jannik, et al.
Publicado: (2023)

He’s Come!!
por: Stewart, A. T.
Publicado: (1869)

Squamous Cell Carcinoma of Skin Cancer Margin Classification From Digital Histopathology Images Using Deep Learning
por: Wako, Beshatu Debela, et al.
Publicado: (2022)

Genomic biomarker of checkpoint efficacy, highways for precision medicine in lung cancer
por: Ghiringhelli, Francois, et al.
Publicado: (2018)

Blood baseline neutrophil count predicts bevacizumab efficacy in glioblastoma
por: Bertaut, Aurélie, et al.
Publicado: (2016)

Artificial classification of cervical squamous lesions in ThinPrep cytologic tests using a deep convolutional neural network
por: Liu, Li, et al.
Publicado: (2020)

Histopathological characteristics of metastasizing squamous cell carcinoma of the skin and lips
por: Quaedvlieg, P J F, et al.
Publicado: (2006)

Histopathological Variants of Cutaneous Squamous Cell Carcinoma: A Review
por: Yanofsky, Valerie R., et al.
Publicado: (2011)

Clinical, Epidemiological And Histopathological Prognostic Factors In Oral Squamous Carcinoma
por: Dragomir, L.P., et al.
Publicado: (2010)

Cytological And Histopathological Aspects Concerning Preinvasive Squamous Cervical Lesions
por: Muntean, Mihaela, et al.
Publicado: (2010)

Synchronous oral squamous cell carcinomas with unusual histopathological feature
por: Kumar, Kiran, et al.
Publicado: (2012)

First-line durvalumab and tremelimumab with chemotherapy in RAS-mutated metastatic colorectal cancer: a phase 1b/2 trial
por: Thibaudin, Marion, et al.
Publicado: (2023)

Deep Learning for the Classification of Non-Hodgkin Lymphoma on Histopathological Images
por: Steinbuss, Georg, et al.
Publicado: (2021)

Insight into Classification and Risk Stratification of Head and Neck Squamous Cell Carcinoma in Era of Emerging Biomarkers with Focus on Histopathologic Parameters
por: Mäkitie, Antti A., et al.
Publicado: (2022)

Molecular Profiling in Non-Squamous Non-Small Cell Lung Carcinoma: Towards a Switch to Next-Generation Sequencing Reflex Testing
por: Pujol, Nina, et al.
Publicado: (2022)

Sumoylation of Hes6 Regulates Protein Degradation and Hes1-Mediated Transcription
por: Lee, Jiwon, et al.
Publicado: (2015)

MER4 endogenous retrovirus correlated with better efficacy of anti-PD1/PD-L1 therapy in non-small cell lung cancer
por: Lecuelle, Julie, et al.
Publicado: (2022)

Histopathology of Women with “Atypical Squamous Cells Cannot Exclude High-Grade Squamous Intraepithelial Lesion” (ASC-H) Smears
por: Ratree, Sasivimon, et al.
Publicado: (2019)

An Efficient Combination of Convolutional Neural Network and LightGBM Algorithm for Lung Cancer Histopathology Classification
por: Hamed, Esraa A.-R., et al.
Publicado: (2023)

Convolutional neural networks for classification of alignments of non-coding RNA sequences
por: Aoki, Genta, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_27qdq1rbsbf70u630d1qludmre