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Phytomedicine in Disease Management: In-Silico Analysis of the Binding Affinity of Artesunate and Azadirachtin for Malaria Treatment

In the rural communities of sub-Saharan African (sSA) countries, malaria is being managed using phytocompounds. Artesunate is reported to inhibit Gephyrin E, a central, multi-domain scaffolding protein of inhibitory post-synapses. Neem plant and its metabolites like azadirachtin are being indicated...

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Detalles Bibliográficos
Autores principales: Okoh, Michael P., Singla, Rajeev K., Madu, Chijioke, Soremekun, Opeyemi, Adejoh, Johnson, Alli, Lukman A., Shen, Bairong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669099/
https://www.ncbi.nlm.nih.gov/pubmed/34916935
http://dx.doi.org/10.3389/fphar.2021.751032

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