Glutathione synthesis primes monocytes metabolic and epigenetic pathway for β-glucan-trained immunity

Trained monocytes and macrophages produce reactive oxygen species (ROS), which trigger antioxidative glutathione (GSH) response to buffer the rising ROS. However, whether and how the trained immunity is shaped by GSH synthesis remains unknown. Here, we report that β-glucan-trained macrophages from m...

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Detalles Bibliográficos
Autores principales: Su, Haibo, Huang, Jiaxin, Weng, Shufeng, Zhang, Baoying, Zhang, Tianran, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669111/
https://www.ncbi.nlm.nih.gov/pubmed/34894475
http://dx.doi.org/10.1016/j.redox.2021.102206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669111/
https://www.ncbi.nlm.nih.gov/pubmed/34894475
http://dx.doi.org/10.1016/j.redox.2021.102206

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