A Genome-Wide CRISPR/Cas9-Based Screen Identifies Heparan Sulfate Proteoglycans as Ligands of Killer-Cell Immunoglobulin-Like Receptors

While human leukocyte antigen (HLA) and HLA-like proteins comprise an overwhelming majority of known ligands for NK-cell receptors, the interactions of NK-cell receptors with non-conventional ligands, particularly carbohydrate antigens, is less well described. We previously found through a bead-base...

Descripción completa

Detalles Bibliográficos
Autores principales: Klein, Klara, Hölzemer, Angelique, Wang, Tim, Kim, Tae-Eun, Dugan, Haley L., Jost, Stephanie, Altfeld, Marcus, Garcia-Beltran, Wilfredo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669139/
https://www.ncbi.nlm.nih.gov/pubmed/34917099
http://dx.doi.org/10.3389/fimmu.2021.798235

Ejemplares similares

Ejemplares similares