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Isolated Superior Mesenteric Artery Dissection After Methamphetamine Use: A Rare Adverse Effect

Methamphetamine is the second most commonly abused drug worldwide. It is a sympathomimetic agent that works by inhibiting the reuptake of monoamine neurotransmitters, including dopamine, norepinephrine, and serotonin. Methamphetamine use is associated with early mortality, and cardiovascular complic...

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Autores principales: Alzahrani, Rayan A, Alzahrani, Omar M, Alherz, Sarah H, Alzahrani, Abdulrahman A, Alzahrani, Omran M, Alqarni, Mohammed A, Alzahrani, Khalid Abdulrahman A, Alzahrani, Khalid Abdulkarim H, Al Zahrani, Suhayb A, Alzahrani, Abdulaziz A, Alghamdi, Hamad A, Alshammari, Malak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669146/
https://www.ncbi.nlm.nih.gov/pubmed/34917433
http://dx.doi.org/10.7759/cureus.19551
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author Alzahrani, Rayan A
Alzahrani, Omar M
Alherz, Sarah H
Alzahrani, Abdulrahman A
Alzahrani, Omran M
Alqarni, Mohammed A
Alzahrani, Khalid Abdulrahman A
Alzahrani, Khalid Abdulkarim H
Al Zahrani, Suhayb A
Alzahrani, Abdulaziz A
Alghamdi, Hamad A
Alshammari, Malak
author_facet Alzahrani, Rayan A
Alzahrani, Omar M
Alherz, Sarah H
Alzahrani, Abdulrahman A
Alzahrani, Omran M
Alqarni, Mohammed A
Alzahrani, Khalid Abdulrahman A
Alzahrani, Khalid Abdulkarim H
Al Zahrani, Suhayb A
Alzahrani, Abdulaziz A
Alghamdi, Hamad A
Alshammari, Malak
author_sort Alzahrani, Rayan A
collection PubMed
description Methamphetamine is the second most commonly abused drug worldwide. It is a sympathomimetic agent that works by inhibiting the reuptake of monoamine neurotransmitters, including dopamine, norepinephrine, and serotonin. Methamphetamine use is associated with early mortality, and cardiovascular complications are the leading cause of increased mortality. We discuss the case of a 41-year-old man who presented to the emergency department with a sudden abdominal pain of eight hours' duration. The pain was located in the epigastric area with radiation to the back. Upon examination, the patient appeared agitated and diaphoretic. His pupils were dilated bilaterally. His vital signs included tachycardia (120 bpm), tachypnea (24 bpm), hypertension (150/90 mmHg), and normal temperature (36.9 ℃). Abdominal examination revealed a soft and lax abdomen with no tenderness. His bowel sounds were normal. Given the physical signs, a toxicology screen was conducted and was positive for methamphetamine use. The patient reported that he used recreational drugs occasionally and admitted that the abdominal pain developed a few hours following methamphetamine use. The patient was treated with fluid resuscitation, analgesic, antihypertension medications, and anticoagulant therapy. The patient had significant improvement in his condition within 48 hours with complete resolution of the abdominal pain. Isolated superior mesenteric artery dissection is a very rare clinical condition. This case report highlights the importance of recognizing the cardiovascular adverse effects that may develop after methamphetamine use.
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spelling pubmed-86691462021-12-15 Isolated Superior Mesenteric Artery Dissection After Methamphetamine Use: A Rare Adverse Effect Alzahrani, Rayan A Alzahrani, Omar M Alherz, Sarah H Alzahrani, Abdulrahman A Alzahrani, Omran M Alqarni, Mohammed A Alzahrani, Khalid Abdulrahman A Alzahrani, Khalid Abdulkarim H Al Zahrani, Suhayb A Alzahrani, Abdulaziz A Alghamdi, Hamad A Alshammari, Malak Cureus Cardiac/Thoracic/Vascular Surgery Methamphetamine is the second most commonly abused drug worldwide. It is a sympathomimetic agent that works by inhibiting the reuptake of monoamine neurotransmitters, including dopamine, norepinephrine, and serotonin. Methamphetamine use is associated with early mortality, and cardiovascular complications are the leading cause of increased mortality. We discuss the case of a 41-year-old man who presented to the emergency department with a sudden abdominal pain of eight hours' duration. The pain was located in the epigastric area with radiation to the back. Upon examination, the patient appeared agitated and diaphoretic. His pupils were dilated bilaterally. His vital signs included tachycardia (120 bpm), tachypnea (24 bpm), hypertension (150/90 mmHg), and normal temperature (36.9 ℃). Abdominal examination revealed a soft and lax abdomen with no tenderness. His bowel sounds were normal. Given the physical signs, a toxicology screen was conducted and was positive for methamphetamine use. The patient reported that he used recreational drugs occasionally and admitted that the abdominal pain developed a few hours following methamphetamine use. The patient was treated with fluid resuscitation, analgesic, antihypertension medications, and anticoagulant therapy. The patient had significant improvement in his condition within 48 hours with complete resolution of the abdominal pain. Isolated superior mesenteric artery dissection is a very rare clinical condition. This case report highlights the importance of recognizing the cardiovascular adverse effects that may develop after methamphetamine use. Cureus 2021-11-13 /pmc/articles/PMC8669146/ /pubmed/34917433 http://dx.doi.org/10.7759/cureus.19551 Text en Copyright © 2021, Alzahrani et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiac/Thoracic/Vascular Surgery
Alzahrani, Rayan A
Alzahrani, Omar M
Alherz, Sarah H
Alzahrani, Abdulrahman A
Alzahrani, Omran M
Alqarni, Mohammed A
Alzahrani, Khalid Abdulrahman A
Alzahrani, Khalid Abdulkarim H
Al Zahrani, Suhayb A
Alzahrani, Abdulaziz A
Alghamdi, Hamad A
Alshammari, Malak
Isolated Superior Mesenteric Artery Dissection After Methamphetamine Use: A Rare Adverse Effect
title Isolated Superior Mesenteric Artery Dissection After Methamphetamine Use: A Rare Adverse Effect
title_full Isolated Superior Mesenteric Artery Dissection After Methamphetamine Use: A Rare Adverse Effect
title_fullStr Isolated Superior Mesenteric Artery Dissection After Methamphetamine Use: A Rare Adverse Effect
title_full_unstemmed Isolated Superior Mesenteric Artery Dissection After Methamphetamine Use: A Rare Adverse Effect
title_short Isolated Superior Mesenteric Artery Dissection After Methamphetamine Use: A Rare Adverse Effect
title_sort isolated superior mesenteric artery dissection after methamphetamine use: a rare adverse effect
topic Cardiac/Thoracic/Vascular Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669146/
https://www.ncbi.nlm.nih.gov/pubmed/34917433
http://dx.doi.org/10.7759/cureus.19551
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