Targeting the “sweet spot” in septic shock – A perspective on the endothelial glycocalyx regulating proteins Heparanase-1 and -2

Sepsis is a life-threatening syndrome caused by a pathological host response to an infection that eventually, if uncontrolled, leads to septic shock and ultimately, death. In sepsis, a massive aggregation of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAM...

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Detalles Bibliográficos
Autores principales: Pape, Thorben, Hunkemöller, Anna Maria, Kümpers, Philipp, Haller, Hermann, David, Sascha, Stahl, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Special Section on The Glycocalyx: Pathobiology and Repair; Edited by Jillian Richter & Ralph Sanderson.
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669377/
https://www.ncbi.nlm.nih.gov/pubmed/34917926
http://dx.doi.org/10.1016/j.mbplus.2021.100095

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