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Life-threatening complications of streptococcal sepsis: a PICU contemporary series
BACKGROUND: Life-threatening streptococcal sepsis nowadays represents an uncommon event in previously healthy infants and children. Critically ill patients suffering from severe streptococcal sepsis complications may present with pre-antibiotic era clinical pictures and require a timely clinical app...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669399/ https://www.ncbi.nlm.nih.gov/pubmed/37386530 http://dx.doi.org/10.1186/s44158-021-00028-1 |
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author | Piastra, M. Ferrari, V. Picconi, E. Morena, T. C. Pezza, L. De Rosa, G. Fedele, M. C. Genovese, O. Onesimo, R. Tempera, A. Valentini, P. Buonsenso, D. Visconti, F. Zito, G. Benassi, C. Conti, G. |
author_facet | Piastra, M. Ferrari, V. Picconi, E. Morena, T. C. Pezza, L. De Rosa, G. Fedele, M. C. Genovese, O. Onesimo, R. Tempera, A. Valentini, P. Buonsenso, D. Visconti, F. Zito, G. Benassi, C. Conti, G. |
author_sort | Piastra, M. |
collection | PubMed |
description | BACKGROUND: Life-threatening streptococcal sepsis nowadays represents an uncommon event in previously healthy infants and children. Critically ill patients suffering from severe streptococcal sepsis complications may present with pre-antibiotic era clinical pictures and require a timely clinical approach to achieve restitutio ad integrum. RESULTS: We report a series of four patient groups affected by an uncommon life-threatening streptococcal sepsis, each of them exhibiting some distinct features. Streptococcus Agalactiae sepsis was associated with cerebral thrombotic/ischaemic lesions, whereas severe cardiogenic shock was prominent in the Streptococcus Viridans group; Streptococcus Faecalis and β-hemolytic group A Streptococcus patients mostly reported lung complications. CONCLUSIONS: Previous antibiotic treatments should not delay aggressive treatment in the intensive care setting. Early diagnostic suspicion, as well as appropriate and aggressive treatment provided within an intensive care setting are crucial for the clinical outcome. |
format | Online Article Text |
id | pubmed-8669399 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-86693992021-12-14 Life-threatening complications of streptococcal sepsis: a PICU contemporary series Piastra, M. Ferrari, V. Picconi, E. Morena, T. C. Pezza, L. De Rosa, G. Fedele, M. C. Genovese, O. Onesimo, R. Tempera, A. Valentini, P. Buonsenso, D. Visconti, F. Zito, G. Benassi, C. Conti, G. J Anesth Analg Crit Care Original Article BACKGROUND: Life-threatening streptococcal sepsis nowadays represents an uncommon event in previously healthy infants and children. Critically ill patients suffering from severe streptococcal sepsis complications may present with pre-antibiotic era clinical pictures and require a timely clinical approach to achieve restitutio ad integrum. RESULTS: We report a series of four patient groups affected by an uncommon life-threatening streptococcal sepsis, each of them exhibiting some distinct features. Streptococcus Agalactiae sepsis was associated with cerebral thrombotic/ischaemic lesions, whereas severe cardiogenic shock was prominent in the Streptococcus Viridans group; Streptococcus Faecalis and β-hemolytic group A Streptococcus patients mostly reported lung complications. CONCLUSIONS: Previous antibiotic treatments should not delay aggressive treatment in the intensive care setting. Early diagnostic suspicion, as well as appropriate and aggressive treatment provided within an intensive care setting are crucial for the clinical outcome. BioMed Central 2021-12-14 /pmc/articles/PMC8669399/ /pubmed/37386530 http://dx.doi.org/10.1186/s44158-021-00028-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Piastra, M. Ferrari, V. Picconi, E. Morena, T. C. Pezza, L. De Rosa, G. Fedele, M. C. Genovese, O. Onesimo, R. Tempera, A. Valentini, P. Buonsenso, D. Visconti, F. Zito, G. Benassi, C. Conti, G. Life-threatening complications of streptococcal sepsis: a PICU contemporary series |
title | Life-threatening complications of streptococcal sepsis: a PICU contemporary series |
title_full | Life-threatening complications of streptococcal sepsis: a PICU contemporary series |
title_fullStr | Life-threatening complications of streptococcal sepsis: a PICU contemporary series |
title_full_unstemmed | Life-threatening complications of streptococcal sepsis: a PICU contemporary series |
title_short | Life-threatening complications of streptococcal sepsis: a PICU contemporary series |
title_sort | life-threatening complications of streptococcal sepsis: a picu contemporary series |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669399/ https://www.ncbi.nlm.nih.gov/pubmed/37386530 http://dx.doi.org/10.1186/s44158-021-00028-1 |
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