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Rotavirus NSP1 Contributes to Intestinal Viral Replication, Pathogenesis, and Transmission

Rotavirus (RV)-encoded nonstructural protein 1 (NSP1), the product of gene segment 5, effectively antagonizes host interferon (IFN) signaling via multiple mechanisms. Recent studies with the newly established RV reverse genetics system indicate that NSP1 is not essential for the replication of the s...

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Detalles Bibliográficos
Autores principales: Hou, Gaopeng, Zeng, Qiru, Matthijnssens, Jelle, Greenberg, Harry B., Ding, Siyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669464/
https://www.ncbi.nlm.nih.gov/pubmed/34903043
http://dx.doi.org/10.1128/mBio.03208-21

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