Myeloid-Derived Suppressor Cells Mediate T Cell Dysfunction in Nonhuman Primate TB Granulomas

Myeloid-derived suppressor cells (MDSCs) represent an innate immune cell population comprised of immature myeloid cells and myeloid progenitors with very potent immunosuppressive potential. MDSCs are reported to be abundant in the lungs of active tuberculosis (TB) patients. We sought to perform an i...

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Detalles Bibliográficos
Autores principales: Singh, Bindu, Singh, Dhiraj K., Ganatra, Shashank R., Escobedo, Ruby A., Khader, Shabaana, Schlesinger, Larry S., Kaushal, Deepak, Mehra, Smriti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669465/
https://www.ncbi.nlm.nih.gov/pubmed/34903057
http://dx.doi.org/10.1128/mbio.03189-21

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