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Usher syndrome type 1-associated gene, pcdh15b, is required for photoreceptor structural integrity in zebrafish

Blindness associated with Usher syndrome type 1 (USH1) is typically characterized as rod photoreceptor degeneration, followed by secondary loss of cones. The mechanisms leading to blindness are unknown because most genetic mouse models only recapitulate auditory defects. We generated zebrafish mutan...

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Detalles Bibliográficos
Autores principales: Miles, Amanda, Blair, Clarke, Emili, Andrew, Tropepe, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669488/
https://www.ncbi.nlm.nih.gov/pubmed/34668518
http://dx.doi.org/10.1242/dmm.048965

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