IFT trains overcome an NPHP module barrier at the transition zone

Cilia harbor diffusion barriers for soluble and membrane proteins within their proximal-most transition zone (TZ) region and employ an intraflagellar transport (IFT) system to form dynamic motile and signaling compartments. In this issue, De-Castro and colleagues (2021. J. Cell Biol. https://doi.org...

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Detalles Bibliográficos
Autores principales: Park, Kwangjin, Leroux, Michel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669515/
https://www.ncbi.nlm.nih.gov/pubmed/34889953
http://dx.doi.org/10.1083/jcb.202112015
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author Park, Kwangjin
Leroux, Michel R.
author_facet Park, Kwangjin
Leroux, Michel R.
author_sort Park, Kwangjin
collection PubMed
description Cilia harbor diffusion barriers for soluble and membrane proteins within their proximal-most transition zone (TZ) region and employ an intraflagellar transport (IFT) system to form dynamic motile and signaling compartments. In this issue, De-Castro and colleagues (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202010178) uncover a long-suspected role for the TZ in gating IFT particles.
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spelling pubmed-86695152022-07-03 IFT trains overcome an NPHP module barrier at the transition zone Park, Kwangjin Leroux, Michel R. J Cell Biol Spotlight Cilia harbor diffusion barriers for soluble and membrane proteins within their proximal-most transition zone (TZ) region and employ an intraflagellar transport (IFT) system to form dynamic motile and signaling compartments. In this issue, De-Castro and colleagues (2021. J. Cell Biol. https://doi.org/10.1083/jcb.202010178) uncover a long-suspected role for the TZ in gating IFT particles. Rockefeller University Press 2021-12-10 /pmc/articles/PMC8669515/ /pubmed/34889953 http://dx.doi.org/10.1083/jcb.202112015 Text en © 2021 Park and Leroux https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
Park, Kwangjin
Leroux, Michel R.
IFT trains overcome an NPHP module barrier at the transition zone
title IFT trains overcome an NPHP module barrier at the transition zone
title_full IFT trains overcome an NPHP module barrier at the transition zone
title_fullStr IFT trains overcome an NPHP module barrier at the transition zone
title_full_unstemmed IFT trains overcome an NPHP module barrier at the transition zone
title_short IFT trains overcome an NPHP module barrier at the transition zone
title_sort ift trains overcome an nphp module barrier at the transition zone
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669515/
https://www.ncbi.nlm.nih.gov/pubmed/34889953
http://dx.doi.org/10.1083/jcb.202112015
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