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Targeting Splicing Factor SRSF6 for Cancer Therapy

Aberrant alternative splicing of pre-mRNA is an emerging cancer hallmark. Many cancer-associated genes undergo alternative splicing to produce multiple isoforms with diverse or even antagonistic functions. Oncogenic isoforms are often up-regulated, whereas tumor suppressive isoforms are down-regulat...

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Detalles Bibliográficos
Autores principales: She, Wenting, Shao, Jun, Jia, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669609/
https://www.ncbi.nlm.nih.gov/pubmed/34917618
http://dx.doi.org/10.3389/fcell.2021.780023

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