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Inhibition of lncRNA NEAT1 protects endothelial cells against hypoxia/reoxygenation-induced NLRP3 inflammasome activation by targeting the miR-204/BRCC3 axis

Cardiovascular ischemia/reperfusion (I/R) injury is primarily caused by oxygen recovery after prolonged hypoxia. Previous studies found that the long non coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) was involved in cardiovascular pathology, and that NOD-like receptor protein 3...

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Detalles Bibliográficos
Autores principales: Yao, Tao, Song, Yiting, Li, Shutao, Gu, Jing, Yan, Xuetao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669661/
https://www.ncbi.nlm.nih.gov/pubmed/34850961
http://dx.doi.org/10.3892/mmr.2021.12548