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G Protein-Coupled Receptor GPR35 Suppresses Lipid Accumulation in Hepatocytes

[Image: see text] Although prevalent, nonalcoholic fatty liver disease is not currently treated effectively with medicines. Initially, using wild-type and genome-edited clones of the human hepatocyte cell line HepG2, we show that activation of the orphan G protein-coupled receptor GPR35 is both able...

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Detalles Bibliográficos
Autores principales:	Lin, Li-Chiung, Quon, Tezz, Engberg, Susanna, Mackenzie, Amanda E., Tobin, Andrew B., Milligan, Graeme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669712/ https://www.ncbi.nlm.nih.gov/pubmed/34927014 http://dx.doi.org/10.1021/acsptsci.1c00224

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