The spike protein of SARS-CoV-2 induces heme oxygenase-1: Pathophysiologic implications

BACKGROUND: Acute kidney injury (AKI) is both a consequence and determinant of outcomes in COVID-19. The kidney is one of the major organs infected by the causative virus, SARS-CoV-2. Viral entry into cells requires the viral spike protein, and both the virus and its spike protein appear in the urin...

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Detalles Bibliográficos
Autores principales: Singh, Raman Deep, Barry, Michael A., Croatt, Anthony J., Ackerman, Allan W., Grande, Joseph P., Diaz, Rosa M., Vile, Richard G., Agarwal, Anupam, Nath, Karl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669938/
https://www.ncbi.nlm.nih.gov/pubmed/34920080
http://dx.doi.org/10.1016/j.bbadis.2021.166322

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