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Type I Interferon and the Spectrum of Susceptibility to Viral Infection and Autoimmune Disease: A Shared Genomic Signature

Type I interferons (IFN-I) and their cognate receptor, the IFNAR1/2 heterodimer, are critical components of the innate immune system in humans. They have been widely explored in the context of viral infection and autoimmune disease where they play key roles in protection against infection or shaping...

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Detalles Bibliográficos
Autores principales: Sugrue, Jamie A., Bourke, Nollaig M., O’Farrelly, Cliona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669998/
https://www.ncbi.nlm.nih.gov/pubmed/34917078
http://dx.doi.org/10.3389/fimmu.2021.757249