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Type I Interferon and the Spectrum of Susceptibility to Viral Infection and Autoimmune Disease: A Shared Genomic Signature
Type I interferons (IFN-I) and their cognate receptor, the IFNAR1/2 heterodimer, are critical components of the innate immune system in humans. They have been widely explored in the context of viral infection and autoimmune disease where they play key roles in protection against infection or shaping...
Autores principales: | Sugrue, Jamie A., Bourke, Nollaig M., O’Farrelly, Cliona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669998/ https://www.ncbi.nlm.nih.gov/pubmed/34917078 http://dx.doi.org/10.3389/fimmu.2021.757249 |
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