Trim28 acts as restriction factor of prototype foamy virus replication by modulating H3K9me3 marks and destabilizing the viral transactivator Tas

BACKGROUND: Prototype foamy virus (PFV) is nonpathogenic complex retroviruses that express a transcriptional transactivator Tas, which is essential for the activity of viral long terminal repeat (LTR) promoter and internal promoter (IP). Tripartite motif-containing protein 28 (Trim28) is well known...

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Detalles Bibliográficos
Autores principales: Yuan, Peipei, Yan, Jun, Wang, Shuang, Guo, Yang, Xi, Xueyan, Han, Song, Yin, Jun, Peng, Biwen, He, Xiaohua, Bodem, Jochen, Liu, Wanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670036/
https://www.ncbi.nlm.nih.gov/pubmed/34903241
http://dx.doi.org/10.1186/s12977-021-00584-y

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