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Increased susceptibility of cystic fibrosis airway epithelial cells to ferroptosis
BACKGROUND: Defective chloride transport in airway epithelial cells (AECs) and the associated lung disease are the main causes of morbidity and early mortality in cystic fibrosis (CF). Abnormal airway iron homeostasis and the presence of lipid peroxidation products, indicative of oxidative stress, a...
Autores principales: | Maniam, Pramila, Essilfie, Ama-Tawiah, Kalimutho, Murugan, Ling, Dora, Frazer, David M., Phipps, Simon, Anderson, Gregory J., Reid, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670191/ https://www.ncbi.nlm.nih.gov/pubmed/34903297 http://dx.doi.org/10.1186/s40659-021-00361-3 |
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