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Landscape of HER2-low metastatic breast cancer (MBC): results from the Austrian AGMT_MBC-Registry
BACKGROUND: About 50% of all primary breast cancers show a low-level expression of HER2 (HER2-low), defined as immunohistochemically 1+ or 2+ and lack of HER2 gene amplification measured by in situ hybridization. This low HER2 expression is a promising new target for antibody–drug conjugates (ADCs)...
Autores principales: | Gampenrieder, Simon Peter, Rinnerthaler, Gabriel, Tinchon, Christoph, Petzer, Andreas, Balic, Marija, Heibl, Sonja, Schmitt, Clemens, Zabernigg, August Felix, Egle, Daniel, Sandholzer, Margit, Singer, Christian Fridolin, Roitner, Florian, Hager, Christopher, Andel, Johannes, Hubalek, Michael, Knauer, Michael, Greil, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670265/ https://www.ncbi.nlm.nih.gov/pubmed/34906198 http://dx.doi.org/10.1186/s13058-021-01492-x |
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