IRAK1-regulated IFN-γ signaling induces MDSC to facilitate immune evasion in FGFR1-driven hematological malignancies

BACKGROUND: Stem Cell leukemia/lymphoma syndrome (SCLL) presents as a myeloproliferative disease which can progress to acute myeloid leukemia and is associated with the coincident development of B-cell and T-cell lymphomas. SCLL is driven by the constitutive activation of fibroblast growth factor re...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Baohuan, Liu, Yun, Chong, Yating, Zhang, Hualei, Matsunaga, Atsuko, Fang, Xuexiu, Pacholczyk, Rafal, Zhou, Gang, Cowell, John K., Hu, Tianxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670266/
https://www.ncbi.nlm.nih.gov/pubmed/34906138
http://dx.doi.org/10.1186/s12943-021-01460-1

Ejemplares similares

Ejemplares similares