Impact of T cells on neurodegeneration in anti‐GAD65 limbic encephalitis

OBJECTIVE: Direct pathogenic effects of autoantibodies to the 65 kDa isoform of glutamic acid decarboxylase (GAD65) in autoimmune limbic encephalitis (LE) have been questioned due to its intracellular localization. We therefore hypothesized a pathogenic role for T cells. METHODS: We assessed magnet...

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Detalles Bibliográficos
Autores principales: Dik, Andre, Widman, Guido, Schulte‐Mecklenbeck, Andreas, Witt, Juri‐Alexander, Pitsch, Julika, Golombeck, Kristin S., Wagner, Jan, Gallus, Marco, Strippel, Christine, Hansen, Niels, Mönig, Constanze, Räuber, Saskia, Wiendl, Heinz, Elger, Christian E., Surges, Rainer, Meuth, Sven G., Helmstaedter, Christoph, Gross, Catharina C., Becker, Albert J., Melzer, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670322/
https://www.ncbi.nlm.nih.gov/pubmed/34841709
http://dx.doi.org/10.1002/acn3.51486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670322/
https://www.ncbi.nlm.nih.gov/pubmed/34841709
http://dx.doi.org/10.1002/acn3.51486

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