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Impact of T cells on neurodegeneration in anti‐GAD65 limbic encephalitis
OBJECTIVE: Direct pathogenic effects of autoantibodies to the 65 kDa isoform of glutamic acid decarboxylase (GAD65) in autoimmune limbic encephalitis (LE) have been questioned due to its intracellular localization. We therefore hypothesized a pathogenic role for T cells. METHODS: We assessed magnet...
Autores principales: | Dik, Andre, Widman, Guido, Schulte‐Mecklenbeck, Andreas, Witt, Juri‐Alexander, Pitsch, Julika, Golombeck, Kristin S., Wagner, Jan, Gallus, Marco, Strippel, Christine, Hansen, Niels, Mönig, Constanze, Räuber, Saskia, Wiendl, Heinz, Elger, Christian E., Surges, Rainer, Meuth, Sven G., Helmstaedter, Christoph, Gross, Catharina C., Becker, Albert J., Melzer, Nico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670322/ https://www.ncbi.nlm.nih.gov/pubmed/34841709 http://dx.doi.org/10.1002/acn3.51486 |
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