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Amelanotic metastatic gastric malignant melanoma: a case report
Melanoma is a malignant form of cutaneous cancer with an increasing incidence since 1970s, accounting for nearly 75% of the death related to skin cancer especially in western countries. Highest recurrence and mortality were observed for the subtype with distal metastasis, demonstrating poor outcomes...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670341/ https://www.ncbi.nlm.nih.gov/pubmed/34459456 http://dx.doi.org/10.1097/CAD.0000000000001227 |
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author | Zhu, Min Zhang, Da-ya Zhang, Guan-jun Wang, Zhan-bo Lid, Ming-yang |
author_facet | Zhu, Min Zhang, Da-ya Zhang, Guan-jun Wang, Zhan-bo Lid, Ming-yang |
author_sort | Zhu, Min |
collection | PubMed |
description | Melanoma is a malignant form of cutaneous cancer with an increasing incidence since 1970s, accounting for nearly 75% of the death related to skin cancer especially in western countries. Highest recurrence and mortality were observed for the subtype with distal metastasis, demonstrating poor outcomes. However, high incidence of gastrointestinal metastasis of malignant melanoma is frequently misdiagnosed due to lack of specific clinical manifestations, especially for the rare observed cases presented amelanotic appearance, accounting for about 2% of all metastatic cases. In the present study, we reported a 36-year-old male patient, who was firstly diagnosed as gastric cancer, and then was confirmed as amelanotic melanoma metastasis by pathological examination, demonstrating positive for melanoma markers including Melan A, S-100, Hmb45 and CD79a. In conclusion, for the amelanotic neoplasm observed during gastroscopy in patients with melanoma history, pathological examination should be carried out to confirm the possibility of melanoma metastasis, providing evidences for the following treatment. |
format | Online Article Text |
id | pubmed-8670341 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-86703412021-12-15 Amelanotic metastatic gastric malignant melanoma: a case report Zhu, Min Zhang, Da-ya Zhang, Guan-jun Wang, Zhan-bo Lid, Ming-yang Anticancer Drugs Case Reports Melanoma is a malignant form of cutaneous cancer with an increasing incidence since 1970s, accounting for nearly 75% of the death related to skin cancer especially in western countries. Highest recurrence and mortality were observed for the subtype with distal metastasis, demonstrating poor outcomes. However, high incidence of gastrointestinal metastasis of malignant melanoma is frequently misdiagnosed due to lack of specific clinical manifestations, especially for the rare observed cases presented amelanotic appearance, accounting for about 2% of all metastatic cases. In the present study, we reported a 36-year-old male patient, who was firstly diagnosed as gastric cancer, and then was confirmed as amelanotic melanoma metastasis by pathological examination, demonstrating positive for melanoma markers including Melan A, S-100, Hmb45 and CD79a. In conclusion, for the amelanotic neoplasm observed during gastroscopy in patients with melanoma history, pathological examination should be carried out to confirm the possibility of melanoma metastasis, providing evidences for the following treatment. Lippincott Williams & Wilkins 2021-08-27 2022-01 /pmc/articles/PMC8670341/ /pubmed/34459456 http://dx.doi.org/10.1097/CAD.0000000000001227 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Case Reports Zhu, Min Zhang, Da-ya Zhang, Guan-jun Wang, Zhan-bo Lid, Ming-yang Amelanotic metastatic gastric malignant melanoma: a case report |
title | Amelanotic metastatic gastric malignant melanoma: a case report |
title_full | Amelanotic metastatic gastric malignant melanoma: a case report |
title_fullStr | Amelanotic metastatic gastric malignant melanoma: a case report |
title_full_unstemmed | Amelanotic metastatic gastric malignant melanoma: a case report |
title_short | Amelanotic metastatic gastric malignant melanoma: a case report |
title_sort | amelanotic metastatic gastric malignant melanoma: a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670341/ https://www.ncbi.nlm.nih.gov/pubmed/34459456 http://dx.doi.org/10.1097/CAD.0000000000001227 |
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