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Role of GRK2 in Trophoblast Necroptosis and Spiral Artery Remodeling: Implications for Preeclampsia Pathogenesis

Impaired invasion of extravillous trophoblasts and severe oxidative stress manifest the poor placentation in preeclampsia, which is life-threatening and more than a hypertensive disease of pregnancy. Previous studies have reported that G protein-coupled receptor kinases (GRKs) play a key role in ini...

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Detalles Bibliográficos
Autores principales: Lv, Zi, Xiong, Li-ling, Qin, Xian, Zhang, Hua, Luo, Xin, Peng, Wei, Kilby, Mark D., Saffery, Richard, Baker, Philip N., Qi, Hong-bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670385/
https://www.ncbi.nlm.nih.gov/pubmed/34917606
http://dx.doi.org/10.3389/fcell.2021.694261