Cargando…
Linking function to global and local dynamics in an elevator-type transporter
Transporters cycle through large structural changes to translocate molecules across biological membranes. The temporal relationships between these changes and function, and the molecular properties setting their rates, determine transport efficiency—yet remain mostly unknown. Using single-molecule f...
Autores principales: | Ciftci, Didar, Martens, Chloe, Ghani, Vishnu G., Blanchard, Scott C., Politis, Argyris, Huysmans, Gerard H. M., Boudker, Olga |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670510/ https://www.ncbi.nlm.nih.gov/pubmed/34873050 http://dx.doi.org/10.1073/pnas.2025520118 |
Ejemplares similares
-
The high‐energy transition state of the glutamate transporter homologue GltPh
por: Huysmans, Gerard H M, et al.
Publicado: (2020) -
Single-molecule transport kinetics of a glutamate transporter homolog shows static disorder
por: Ciftci, Didar, et al.
Publicado: (2020) -
The archaeal glutamate transporter homologue Glt(Ph) shows heterogeneous substrate binding
por: Reddy, Krishna D., et al.
Publicado: (2022) -
Millisecond dynamics of an unlabeled amino acid transporter
por: Matin, Tina R., et al.
Publicado: (2020) -
Transport dynamics in a glutamate transporter homologue
por: Akyuz, Nurunisa, et al.
Publicado: (2013)