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A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland

The goal of this study was to evaluate timeliness of Tick-borne Encephalitis vaccination uptake among adults in Switzerland. In this cross-sectional survey, we collected vaccination records from randomly selected adults 18–79 throughout Switzerland. Of 4,626 participants, data from individuals recei...

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Autores principales: Zens, Kyra D., Baroutsou, Vasiliki, Sinniger, Philipp, Lang, Phung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670666/
https://www.ncbi.nlm.nih.gov/pubmed/34905534
http://dx.doi.org/10.1371/journal.pone.0247216
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author Zens, Kyra D.
Baroutsou, Vasiliki
Sinniger, Philipp
Lang, Phung
author_facet Zens, Kyra D.
Baroutsou, Vasiliki
Sinniger, Philipp
Lang, Phung
author_sort Zens, Kyra D.
collection PubMed
description The goal of this study was to evaluate timeliness of Tick-borne Encephalitis vaccination uptake among adults in Switzerland. In this cross-sectional survey, we collected vaccination records from randomly selected adults 18–79 throughout Switzerland. Of 4,626 participants, data from individuals receiving at least 1 TBE vaccination (n = 1875) were evaluated. We determined year and age of first vaccination and vaccine compliance, evaluating dose timeliness. Participants were considered “on time” if they received doses according to the recommended schedule ± a 15% tolerance period. 45% of participants received their first TBE vaccination between 2006 and 2009, which corresponds to a 2006 change in the official recommendation for TBE vaccination in Switzerland. 25% were first vaccinated aged 50+ (mean age 37). More than 95% of individuals receiving the first dose also received the second; ~85% of those receiving the second dose received the third. For individuals completing the primary series, 30% received 3 doses of Encepur, 58% received 3 doses of FSME-Immun, and 12% received a combination. According to “conventional” schedules, 88% and 79% of individuals received their second and third doses “on time”, respectively. 20% of individuals receiving Encepur received their third dose “too early”. Of individuals completing primary vaccination, 19% were overdue for a booster. Among the 31% of subjects receiving a booster, mean time to first booster was 7.1 years. We estimate that a quarter of adults in Switzerland were first vaccinated for TBE aged 50+. Approximately 80% of participants receiving at least one vaccine dose completed the primary series. We further estimate that 66% of individuals completing the TBE vaccination primary series did so with a single vaccine type and adhered to the recommended schedule.
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spelling pubmed-86706662021-12-15 A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland Zens, Kyra D. Baroutsou, Vasiliki Sinniger, Philipp Lang, Phung PLoS One Research Article The goal of this study was to evaluate timeliness of Tick-borne Encephalitis vaccination uptake among adults in Switzerland. In this cross-sectional survey, we collected vaccination records from randomly selected adults 18–79 throughout Switzerland. Of 4,626 participants, data from individuals receiving at least 1 TBE vaccination (n = 1875) were evaluated. We determined year and age of first vaccination and vaccine compliance, evaluating dose timeliness. Participants were considered “on time” if they received doses according to the recommended schedule ± a 15% tolerance period. 45% of participants received their first TBE vaccination between 2006 and 2009, which corresponds to a 2006 change in the official recommendation for TBE vaccination in Switzerland. 25% were first vaccinated aged 50+ (mean age 37). More than 95% of individuals receiving the first dose also received the second; ~85% of those receiving the second dose received the third. For individuals completing the primary series, 30% received 3 doses of Encepur, 58% received 3 doses of FSME-Immun, and 12% received a combination. According to “conventional” schedules, 88% and 79% of individuals received their second and third doses “on time”, respectively. 20% of individuals receiving Encepur received their third dose “too early”. Of individuals completing primary vaccination, 19% were overdue for a booster. Among the 31% of subjects receiving a booster, mean time to first booster was 7.1 years. We estimate that a quarter of adults in Switzerland were first vaccinated for TBE aged 50+. Approximately 80% of participants receiving at least one vaccine dose completed the primary series. We further estimate that 66% of individuals completing the TBE vaccination primary series did so with a single vaccine type and adhered to the recommended schedule. Public Library of Science 2021-12-14 /pmc/articles/PMC8670666/ /pubmed/34905534 http://dx.doi.org/10.1371/journal.pone.0247216 Text en © 2021 Zens et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Zens, Kyra D.
Baroutsou, Vasiliki
Sinniger, Philipp
Lang, Phung
A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland
title A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland
title_full A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland
title_fullStr A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland
title_full_unstemmed A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland
title_short A cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in Switzerland
title_sort cross-sectional study evaluating tick-borne encephalitis vaccine uptake and timeliness among adults in switzerland
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670666/
https://www.ncbi.nlm.nih.gov/pubmed/34905534
http://dx.doi.org/10.1371/journal.pone.0247216
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