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Structural systems pharmacology: A framework for integrating metabolic network and structure-based virtual screening for drug discovery against bacteria

Advances in genome-scale metabolic models (GEMs) and computational drug discovery have caused the identification of drug targets at the system-level and inhibitors to combat bacterial infection and drug resistance. Here we report a structural systems pharmacology framework that integrates the GEM an...

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Detalles Bibliográficos
Autores principales:	Nazarshodeh, Elmira, Marashi, Sayed-Amir, Gharaghani, Sajjad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670682/ https://www.ncbi.nlm.nih.gov/pubmed/34905555 http://dx.doi.org/10.1371/journal.pone.0261267

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