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Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni

BACKGROUND: Schistosoma mansoni histone deacetylase 8 (SmHDAC8) has elicited considerable interest as a target for drug discovery. Invalidation of its transcripts by RNAi leads to impaired survival of the worms in infected mice and its inhibition causes cell apoptosis and death. To determine why it...

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Detalles Bibliográficos
Autores principales:	Pagliazzo, Lucile, Caby, Stéphanie, Lancelot, Julien, Salomé-Desnoulez, Sophie, Saliou, Jean-Michel, Heimburg, Tino, Chassat, Thierry, Cailliau, Katia, Sippl, Wolfgang, Vicogne, Jérôme, Pierce, Raymond J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670706/ https://www.ncbi.nlm.nih.gov/pubmed/34843489 http://dx.doi.org/10.1371/journal.pntd.0009503

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