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Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state

It is well recognized that population heterogeneity plays an important role in the spread of epidemics. While individual variations in social activity are often assumed to be persistent, that is, constant in time, here we discuss the consequences of dynamic heterogeneity. By integrating the stochast...

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Autores principales: Tkachenko, Alexei V, Maslov, Sergei, Wang, Tong, Elbana, Ahmed, Wong, George N, Goldenfeld, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670744/
https://www.ncbi.nlm.nih.gov/pubmed/34747698
http://dx.doi.org/10.7554/eLife.68341
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author Tkachenko, Alexei V
Maslov, Sergei
Wang, Tong
Elbana, Ahmed
Wong, George N
Goldenfeld, Nigel
author_facet Tkachenko, Alexei V
Maslov, Sergei
Wang, Tong
Elbana, Ahmed
Wong, George N
Goldenfeld, Nigel
author_sort Tkachenko, Alexei V
collection PubMed
description It is well recognized that population heterogeneity plays an important role in the spread of epidemics. While individual variations in social activity are often assumed to be persistent, that is, constant in time, here we discuss the consequences of dynamic heterogeneity. By integrating the stochastic dynamics of social activity into traditional epidemiological models, we demonstrate the emergence of a new long timescale governing the epidemic, in broad agreement with empirical data. Our stochastic social activity model captures multiple features of real-life epidemics such as COVID-19, including prolonged plateaus and multiple waves, which are transiently suppressed due to the dynamic nature of social activity. The existence of a long timescale due to the interplay between epidemic and social dynamics provides a unifying picture of how a fast-paced epidemic typically will transition to an endemic state.
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spelling pubmed-86707442021-12-15 Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state Tkachenko, Alexei V Maslov, Sergei Wang, Tong Elbana, Ahmed Wong, George N Goldenfeld, Nigel eLife Physics of Living Systems It is well recognized that population heterogeneity plays an important role in the spread of epidemics. While individual variations in social activity are often assumed to be persistent, that is, constant in time, here we discuss the consequences of dynamic heterogeneity. By integrating the stochastic dynamics of social activity into traditional epidemiological models, we demonstrate the emergence of a new long timescale governing the epidemic, in broad agreement with empirical data. Our stochastic social activity model captures multiple features of real-life epidemics such as COVID-19, including prolonged plateaus and multiple waves, which are transiently suppressed due to the dynamic nature of social activity. The existence of a long timescale due to the interplay between epidemic and social dynamics provides a unifying picture of how a fast-paced epidemic typically will transition to an endemic state. eLife Sciences Publications, Ltd 2021-11-08 /pmc/articles/PMC8670744/ /pubmed/34747698 http://dx.doi.org/10.7554/eLife.68341 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication (https://creativecommons.org/publicdomain/zero/1.0/) .
spellingShingle Physics of Living Systems
Tkachenko, Alexei V
Maslov, Sergei
Wang, Tong
Elbana, Ahmed
Wong, George N
Goldenfeld, Nigel
Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state
title Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state
title_full Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state
title_fullStr Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state
title_full_unstemmed Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state
title_short Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state
title_sort stochastic social behavior coupled to covid-19 dynamics leads to waves, plateaus, and an endemic state
topic Physics of Living Systems
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670744/
https://www.ncbi.nlm.nih.gov/pubmed/34747698
http://dx.doi.org/10.7554/eLife.68341
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