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Knockdown of TRIM8 Protects HK-2 Cells Against Hypoxia/Reoxygenation-Induced Injury by Inhibiting Oxidative Stress-Mediated Apoptosis and Pyroptosis via PI3K/Akt Signal Pathway

BACKGROUND: Acute kidney injury (AKI) emerges as an acute and critical disease. Tripartite motif 8 (TRIM8), one number of the TRIM protein family, is proved to participate in ischemia/reperfusion (I/R) injury. However, whether TRIM8 is involved in renal I/R injury and the associated mechanisms are c...

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Detalles Bibliográficos
Autores principales:	Zhang, Bang-Hua, Liu, Hao, Yuan, Yan, Weng, Xiao-Dong, Du, Yang, Chen, Hui, Chen, Zhi-Yuan, Wang, Lei, Liu, Xiu-Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670861/ https://www.ncbi.nlm.nih.gov/pubmed/34916780 http://dx.doi.org/10.2147/DDDT.S333372

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