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Ferulic Acid Alleviates Oxidative Stress-Induced Cardiomyocyte Injury by the Regulation of miR-499-5p/p21 Signal Cascade

OBJECTIVE: To investigate the protective effects and regulatory mechanisms of ferulic acid on oxidative stress-induced cardiomyocyte injury. METHODS: We established a cardiomyocyte oxidative stress cell model by H(2)O(2) treatment and a mouse heart injury model by isoprenaline infusion of male C57BL...

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Detalles Bibliográficos
Autores principales: Sun, Shenghui, Ruan, Yang, Yan, Mingjing, Xu, Kun, Yang, Yao, Shen, Tao, Jin, Zening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670946/
https://www.ncbi.nlm.nih.gov/pubmed/34917156
http://dx.doi.org/10.1155/2021/1921457

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