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Combining CT Images and Clinical Features of Four Periods to Predict Whether Patients Have Rectal Cancer

In this paper, we mainly use random forest and broad learning system (BLS) to predict rectal cancer. A total of 246 participants with computed tomography (CT) image records were enrolled. The total model in the training set (combined with imaging and clinical indicators) has the best prediction resu...

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Autores principales: Feng, Yingyin, Ding, Qi, Meng, Chen, Wang, Wenfeng, Zhang, Jingjing, Lian, Huixiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670968/
https://www.ncbi.nlm.nih.gov/pubmed/34917137
http://dx.doi.org/10.1155/2021/4662061
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author Feng, Yingyin
Ding, Qi
Meng, Chen
Wang, Wenfeng
Zhang, Jingjing
Lian, Huixiu
author_facet Feng, Yingyin
Ding, Qi
Meng, Chen
Wang, Wenfeng
Zhang, Jingjing
Lian, Huixiu
author_sort Feng, Yingyin
collection PubMed
description In this paper, we mainly use random forest and broad learning system (BLS) to predict rectal cancer. A total of 246 participants with computed tomography (CT) image records were enrolled. The total model in the training set (combined with imaging and clinical indicators) has the best prediction result, with the area under the curve (AUC) of 0.999 (95% confidence internal (CI): 0.996–1.000) and the accuracy of 0.990 (95%CI: 0.976–1.000). Model 3, the general model in the test set, has the best prediction result, with the AUC of 0.962 (95%CI: 0.915–1.000) and the accuracy of 0.920 (95%CI: 0.845–0.995). The results of the model using random forest prediction are compared with those using BLS prediction. It can be found that there is no statistical difference between the two results. Our prediction model combined with image features has a good prediction result, and this image feature is the most important among all features. Consequently, we can successfully predict rectal cancer through a combination of the clinical indicators and the comprehensive indicators of CT image characteristics in four different periods (plain scan, vein, artery, and excretion).
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spelling pubmed-86709682021-12-15 Combining CT Images and Clinical Features of Four Periods to Predict Whether Patients Have Rectal Cancer Feng, Yingyin Ding, Qi Meng, Chen Wang, Wenfeng Zhang, Jingjing Lian, Huixiu Comput Intell Neurosci Research Article In this paper, we mainly use random forest and broad learning system (BLS) to predict rectal cancer. A total of 246 participants with computed tomography (CT) image records were enrolled. The total model in the training set (combined with imaging and clinical indicators) has the best prediction result, with the area under the curve (AUC) of 0.999 (95% confidence internal (CI): 0.996–1.000) and the accuracy of 0.990 (95%CI: 0.976–1.000). Model 3, the general model in the test set, has the best prediction result, with the AUC of 0.962 (95%CI: 0.915–1.000) and the accuracy of 0.920 (95%CI: 0.845–0.995). The results of the model using random forest prediction are compared with those using BLS prediction. It can be found that there is no statistical difference between the two results. Our prediction model combined with image features has a good prediction result, and this image feature is the most important among all features. Consequently, we can successfully predict rectal cancer through a combination of the clinical indicators and the comprehensive indicators of CT image characteristics in four different periods (plain scan, vein, artery, and excretion). Hindawi 2021-12-07 /pmc/articles/PMC8670968/ /pubmed/34917137 http://dx.doi.org/10.1155/2021/4662061 Text en Copyright © 2021 Yingyin Feng et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Feng, Yingyin
Ding, Qi
Meng, Chen
Wang, Wenfeng
Zhang, Jingjing
Lian, Huixiu
Combining CT Images and Clinical Features of Four Periods to Predict Whether Patients Have Rectal Cancer
title Combining CT Images and Clinical Features of Four Periods to Predict Whether Patients Have Rectal Cancer
title_full Combining CT Images and Clinical Features of Four Periods to Predict Whether Patients Have Rectal Cancer
title_fullStr Combining CT Images and Clinical Features of Four Periods to Predict Whether Patients Have Rectal Cancer
title_full_unstemmed Combining CT Images and Clinical Features of Four Periods to Predict Whether Patients Have Rectal Cancer
title_short Combining CT Images and Clinical Features of Four Periods to Predict Whether Patients Have Rectal Cancer
title_sort combining ct images and clinical features of four periods to predict whether patients have rectal cancer
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670968/
https://www.ncbi.nlm.nih.gov/pubmed/34917137
http://dx.doi.org/10.1155/2021/4662061
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