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The SP/NK1R System-Mediated ROS Generation in GBM Cells through Inhibiting Glutaredoxin Protein

Altered redox balance is among the main contributing factors developing glioblastoma multiforme (GBM), a highly aggressive grade IV brain tumor. Neuropeptide substance P (SP) plays a key role in modifying the cellular redox environment by activating the neurokinin-1 receptor (NK1R). In this study, w...

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Detalles Bibliográficos
Autores principales:	Mehrabani, Negeen, Vaezi Kakhki, Mohammad Reza, Javid, Hossein, Ebrahimi, Safieh, Hashemy, Seyed Isaac
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670971/ https://www.ncbi.nlm.nih.gov/pubmed/34917417 http://dx.doi.org/10.1155/2021/9966000

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