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Cox-2 Antagonizes the Protective Effect of Sevoflurane on Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis through Inhibiting the Akt Pathway

OBJECTIVE: To uncover the protective role of sevoflurane on hypoxia/reoxygenation-induced cardiomyocyte apoptosis through the protein kinase B (Akt) pathway. METHODS: An in vitro hypoxia/reoxygenation (H/R) model was established in cardiomyocyte cell line H9c2. Sevoflurane (SEV) was administrated in...

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Detalles Bibliográficos
Autores principales:	Guo, Chunyan, Zhang, Lei, Gao, Yaoxing, Sun, Junzhi, Fan, Lingling, Bai, Yuguang, Zhang, Jing, Naren, Gaowa, Yang, Jiwen, Li, Libiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8670977/ https://www.ncbi.nlm.nih.gov/pubmed/34917200 http://dx.doi.org/10.1155/2021/4114593

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