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Testing for cirrhosis
Cirrhosis can be suspected by a thorough clinical assessment, but compensated liver disease is often asymptomatic. Select investigations are therefore critical for identifying patients with advanced liver disease and cirrhosis Biomarkers and validated serum tests can evaluate liver damage and synthe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
NPS MedicineWise
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671021/ https://www.ncbi.nlm.nih.gov/pubmed/35002032 http://dx.doi.org/10.18773/austprescr.2021.053 |
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author | Gupta, Sidhartha Walker, Sarah |
author_facet | Gupta, Sidhartha Walker, Sarah |
author_sort | Gupta, Sidhartha |
collection | PubMed |
description | Cirrhosis can be suspected by a thorough clinical assessment, but compensated liver disease is often asymptomatic. Select investigations are therefore critical for identifying patients with advanced liver disease and cirrhosis Biomarkers and validated serum tests can evaluate liver damage and synthetic function. The ratio of the concentration of aspartate aminotransferase to the platelet count can predict the presence of cirrhosis Non-invasive imaging techniques, from basic ultrasound to elastography, are critical adjuncts to the clinical assessment of cirrhosis. They reduce the need for liver biopsy Careful monitoring, prescribing and appropriate specialist referral are key considerations in cirrhosis management. Early diagnosis can help to improve the outcomes for patients |
format | Online Article Text |
id | pubmed-8671021 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | NPS MedicineWise |
record_format | MEDLINE/PubMed |
spelling | pubmed-86710212022-01-06 Testing for cirrhosis Gupta, Sidhartha Walker, Sarah Aust Prescr Diagnostic Tests Cirrhosis can be suspected by a thorough clinical assessment, but compensated liver disease is often asymptomatic. Select investigations are therefore critical for identifying patients with advanced liver disease and cirrhosis Biomarkers and validated serum tests can evaluate liver damage and synthetic function. The ratio of the concentration of aspartate aminotransferase to the platelet count can predict the presence of cirrhosis Non-invasive imaging techniques, from basic ultrasound to elastography, are critical adjuncts to the clinical assessment of cirrhosis. They reduce the need for liver biopsy Careful monitoring, prescribing and appropriate specialist referral are key considerations in cirrhosis management. Early diagnosis can help to improve the outcomes for patients NPS MedicineWise 2021-12-01 2021-12 /pmc/articles/PMC8671021/ /pubmed/35002032 http://dx.doi.org/10.18773/austprescr.2021.053 Text en (c) NPS MedicineWise https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND) 4.0 License. |
spellingShingle | Diagnostic Tests Gupta, Sidhartha Walker, Sarah Testing for cirrhosis |
title | Testing for cirrhosis |
title_full | Testing for cirrhosis |
title_fullStr | Testing for cirrhosis |
title_full_unstemmed | Testing for cirrhosis |
title_short | Testing for cirrhosis |
title_sort | testing for cirrhosis |
topic | Diagnostic Tests |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671021/ https://www.ncbi.nlm.nih.gov/pubmed/35002032 http://dx.doi.org/10.18773/austprescr.2021.053 |
work_keys_str_mv | AT guptasidhartha testingforcirrhosis AT walkersarah testingforcirrhosis |