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Medullary neuroschistosomiasis in a pediatric patient: a case report

A pediatric patient with neurological deficit was examined using magnetic resonance imaging (MRI]. The images revealed abnormal signal intensity and enhancement of the spinal cord, indicating myelopathy. Identifying the cause of the myelopathy required a differential diagnosis. Images from MRI inclu...

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Autores principales: Kollapen, Kumeshnie, Ebrahim Suleman, Farhana, Smuts, Izelle, Siwela, Lebohang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671095/
https://www.ncbi.nlm.nih.gov/pubmed/34950274
http://dx.doi.org/10.1016/j.radcr.2021.11.018
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author Kollapen, Kumeshnie
Ebrahim Suleman, Farhana
Smuts, Izelle
Siwela, Lebohang
author_facet Kollapen, Kumeshnie
Ebrahim Suleman, Farhana
Smuts, Izelle
Siwela, Lebohang
author_sort Kollapen, Kumeshnie
collection PubMed
description A pediatric patient with neurological deficit was examined using magnetic resonance imaging (MRI]. The images revealed abnormal signal intensity and enhancement of the spinal cord, indicating myelopathy. Identifying the cause of the myelopathy required a differential diagnosis. Images from MRI included a pre-contrast T1 weighted sagittal sequence, which revealed expansion of the distal lumbar spinal cord and conus medullaris from T10-L1. The T2 weighted sagittal sequence revealed patchy areas of hyperintense signal. We did not notice any chronic hemorrhagic products or cysts. Within the field of view, we saw multifocal areas of bladder wall thickening. Sagittal and axial T1 weighted post gadolinium images demonstrated mixed linear and nodular patchy enhancement of the conus medullaris predominantly anteriorly and along the anterior surface of the meninges. On the 18 day of hospitalization, a spinal biopsy revealed the presence of granuloma with non-viable bilharzia ova, and schistosomiasis of the spinal cord was diagnosed. Although uncommon, when it does occur, schistosomiasis has significant implications. Using MRI, the medical team noticed abnormal features that called for a biopsy, and were thus able to differentiate between medullary schistosomiasis and other infective/inflammatory conditions. A prompt diagnosis is vital for initiating early treatment, and avoiding complications and invasive surgery.
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spelling pubmed-86710952021-12-22 Medullary neuroschistosomiasis in a pediatric patient: a case report Kollapen, Kumeshnie Ebrahim Suleman, Farhana Smuts, Izelle Siwela, Lebohang Radiol Case Rep Case Report A pediatric patient with neurological deficit was examined using magnetic resonance imaging (MRI]. The images revealed abnormal signal intensity and enhancement of the spinal cord, indicating myelopathy. Identifying the cause of the myelopathy required a differential diagnosis. Images from MRI included a pre-contrast T1 weighted sagittal sequence, which revealed expansion of the distal lumbar spinal cord and conus medullaris from T10-L1. The T2 weighted sagittal sequence revealed patchy areas of hyperintense signal. We did not notice any chronic hemorrhagic products or cysts. Within the field of view, we saw multifocal areas of bladder wall thickening. Sagittal and axial T1 weighted post gadolinium images demonstrated mixed linear and nodular patchy enhancement of the conus medullaris predominantly anteriorly and along the anterior surface of the meninges. On the 18 day of hospitalization, a spinal biopsy revealed the presence of granuloma with non-viable bilharzia ova, and schistosomiasis of the spinal cord was diagnosed. Although uncommon, when it does occur, schistosomiasis has significant implications. Using MRI, the medical team noticed abnormal features that called for a biopsy, and were thus able to differentiate between medullary schistosomiasis and other infective/inflammatory conditions. A prompt diagnosis is vital for initiating early treatment, and avoiding complications and invasive surgery. Elsevier 2021-12-09 /pmc/articles/PMC8671095/ /pubmed/34950274 http://dx.doi.org/10.1016/j.radcr.2021.11.018 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kollapen, Kumeshnie
Ebrahim Suleman, Farhana
Smuts, Izelle
Siwela, Lebohang
Medullary neuroschistosomiasis in a pediatric patient: a case report
title Medullary neuroschistosomiasis in a pediatric patient: a case report
title_full Medullary neuroschistosomiasis in a pediatric patient: a case report
title_fullStr Medullary neuroschistosomiasis in a pediatric patient: a case report
title_full_unstemmed Medullary neuroschistosomiasis in a pediatric patient: a case report
title_short Medullary neuroschistosomiasis in a pediatric patient: a case report
title_sort medullary neuroschistosomiasis in a pediatric patient: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671095/
https://www.ncbi.nlm.nih.gov/pubmed/34950274
http://dx.doi.org/10.1016/j.radcr.2021.11.018
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