A Study of Gene Expression, Structure, and Contractility of iPSC-Derived Cardiac Myocytes from a Family with Heart Disease due to LMNA Mutation

Genetic mutations to the Lamin A/C gene (LMNA) can cause heart disease, but the mechanisms making cardiac tissues uniquely vulnerable to the mutations remain largely unknown. Further, patients with LMNA mutations have highly variable presentation of heart disease progression and type. In vitro patie...

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Detalles Bibliográficos
Autores principales: Mehrabi, Mehrsa, Morris, Tessa A., Cang, Zixuan, Nguyen, Cecilia H. H., Sha, Yutong, Asad, Mira N., Khachikyan, Nyree, Greene, Taylor L., Becker, Danielle M., Nie, Qing, Zaragoza, Michael V., Grosberg, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671287/
https://www.ncbi.nlm.nih.gov/pubmed/34585335
http://dx.doi.org/10.1007/s10439-021-02850-8

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