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Age-related accumulation of advanced oxidation protein products promotes osteoclastogenesis through disruption of redox homeostasis

Enhanced osteoclastogenesis is one of the major causes of age-related bone loss. Aging is accompanied by accumulation of advanced oxidation protein products (AOPPs). However, whether AOPPs accumulation contributing to the osteoclastogenesis with aging remains unclear. Here, we showed that AOPPs accu...

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Detalles Bibliográficos
Autores principales: Zhuang, Jingshen, Chen, Xuebing, Cai, Guixing, Wu, Dizheng, Tu, Chen, Zhu, Siyuan, Huang, Yusheng, Xu, Ping, Zhong, Zhaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671415/
https://www.ncbi.nlm.nih.gov/pubmed/34907153
http://dx.doi.org/10.1038/s41419-021-04441-w