Metabolic drug survey highlights cancer cell dependencies and vulnerabilities

Interrogation of cellular metabolism with high-throughput screening approaches can unravel contextual biology and identify cancer-specific metabolic vulnerabilities. To systematically study the consequences of distinct metabolic perturbations, we assemble a comprehensive metabolic drug library (CeMM...

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Detalles Bibliográficos
Autores principales: Pemovska, Tea, Bigenzahn, Johannes W., Srndic, Ismet, Lercher, Alexander, Bergthaler, Andreas, César-Razquin, Adrián, Kartnig, Felix, Kornauth, Christoph, Valent, Peter, Staber, Philipp B., Superti-Furga, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671470/
https://www.ncbi.nlm.nih.gov/pubmed/34907165
http://dx.doi.org/10.1038/s41467-021-27329-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671470/
https://www.ncbi.nlm.nih.gov/pubmed/34907165
http://dx.doi.org/10.1038/s41467-021-27329-x

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