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A low-cost and shielding-free ultra-low-field brain MRI scanner
Magnetic resonance imaging is a key diagnostic tool in modern healthcare, yet it can be cost-prohibitive given the high installation, maintenance and operation costs of the machinery. There are approximately seven scanners per million inhabitants and over 90% are concentrated in high-income countrie...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671508/ https://www.ncbi.nlm.nih.gov/pubmed/34907181 http://dx.doi.org/10.1038/s41467-021-27317-1 |
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author | Liu, Yilong Leong, Alex T. L. Zhao, Yujiao Xiao, Linfang Mak, Henry K. F. Tsang, Anderson Chun On Lau, Gary K. K. Leung, Gilberto K. K. Wu, Ed X. |
author_facet | Liu, Yilong Leong, Alex T. L. Zhao, Yujiao Xiao, Linfang Mak, Henry K. F. Tsang, Anderson Chun On Lau, Gary K. K. Leung, Gilberto K. K. Wu, Ed X. |
author_sort | Liu, Yilong |
collection | PubMed |
description | Magnetic resonance imaging is a key diagnostic tool in modern healthcare, yet it can be cost-prohibitive given the high installation, maintenance and operation costs of the machinery. There are approximately seven scanners per million inhabitants and over 90% are concentrated in high-income countries. We describe an ultra-low-field brain MRI scanner that operates using a standard AC power outlet and is low cost to build. Using a permanent 0.055 Tesla Samarium-cobalt magnet and deep learning for cancellation of electromagnetic interference, it requires neither magnetic nor radiofrequency shielding cages. The scanner is compact, mobile, and acoustically quiet during scanning. We implement four standard clinical neuroimaging protocols (T1- and T2-weighted, fluid-attenuated inversion recovery like, and diffusion-weighted imaging) on this system, and demonstrate preliminary feasibility in diagnosing brain tumor and stroke. Such technology has the potential to meet clinical needs at point of care or in low and middle income countries. |
format | Online Article Text |
id | pubmed-8671508 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-86715082022-01-04 A low-cost and shielding-free ultra-low-field brain MRI scanner Liu, Yilong Leong, Alex T. L. Zhao, Yujiao Xiao, Linfang Mak, Henry K. F. Tsang, Anderson Chun On Lau, Gary K. K. Leung, Gilberto K. K. Wu, Ed X. Nat Commun Article Magnetic resonance imaging is a key diagnostic tool in modern healthcare, yet it can be cost-prohibitive given the high installation, maintenance and operation costs of the machinery. There are approximately seven scanners per million inhabitants and over 90% are concentrated in high-income countries. We describe an ultra-low-field brain MRI scanner that operates using a standard AC power outlet and is low cost to build. Using a permanent 0.055 Tesla Samarium-cobalt magnet and deep learning for cancellation of electromagnetic interference, it requires neither magnetic nor radiofrequency shielding cages. The scanner is compact, mobile, and acoustically quiet during scanning. We implement four standard clinical neuroimaging protocols (T1- and T2-weighted, fluid-attenuated inversion recovery like, and diffusion-weighted imaging) on this system, and demonstrate preliminary feasibility in diagnosing brain tumor and stroke. Such technology has the potential to meet clinical needs at point of care or in low and middle income countries. Nature Publishing Group UK 2021-12-14 /pmc/articles/PMC8671508/ /pubmed/34907181 http://dx.doi.org/10.1038/s41467-021-27317-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Liu, Yilong Leong, Alex T. L. Zhao, Yujiao Xiao, Linfang Mak, Henry K. F. Tsang, Anderson Chun On Lau, Gary K. K. Leung, Gilberto K. K. Wu, Ed X. A low-cost and shielding-free ultra-low-field brain MRI scanner |
title | A low-cost and shielding-free ultra-low-field brain MRI scanner |
title_full | A low-cost and shielding-free ultra-low-field brain MRI scanner |
title_fullStr | A low-cost and shielding-free ultra-low-field brain MRI scanner |
title_full_unstemmed | A low-cost and shielding-free ultra-low-field brain MRI scanner |
title_short | A low-cost and shielding-free ultra-low-field brain MRI scanner |
title_sort | low-cost and shielding-free ultra-low-field brain mri scanner |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671508/ https://www.ncbi.nlm.nih.gov/pubmed/34907181 http://dx.doi.org/10.1038/s41467-021-27317-1 |
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