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CRISPR/Cas9 genome-wide screening identifies LUC7L2 that promotes radioresistance via autophagy in nasopharyngeal carcinoma cells

Radioresistance emerges as the major obstacle to nasopharyngeal carcinoma (NPC) treatment, further understanding of underlying mechanisms is necessary to overcome the radioresistance and improve the therapeutic effect. In this study, we first identified a candidate radioresistant-related gene LUC7L2...

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Detalles Bibliográficos
Autores principales: Shen, Lin, Li, Chao, Chen, Fang, Shen, Liangfang, Li, Zhanzhan, Li, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671510/
https://www.ncbi.nlm.nih.gov/pubmed/34907164
http://dx.doi.org/10.1038/s41420-021-00783-8