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Assessment of genome packaging in AAVs using Orbitrap-based charge-detection mass spectrometry

Adeno-associated viruses (AAVs) represent important gene therapy vectors with several approved clinical applications and numerous more in clinical trials. Genome packaging is an essential step in the bioprocessing of AAVs and needs to be tightly monitored to ensure the proper delivery of transgenes...

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Detalles Bibliográficos
Autores principales:	Wörner, Tobias P., Snijder, Joost, Friese, Olga, Powers, Thomas, Heck, Albert J.R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671526/ https://www.ncbi.nlm.nih.gov/pubmed/34977271 http://dx.doi.org/10.1016/j.omtm.2021.11.013

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