Evaluation of anticancer activity in vitro of a stable copper(I) complex with phosphine-peptide conjugate

[CuI(2,9-dimethyl-1,10-phenanthroline)P(p-OCH(3)-Ph)(2)CH(2)SarcosineGlycine] (1-MPSG), highly stable in physiological media phosphino copper(I) complex—is proposed herein as a viable alternative to anticancer platinum-based drugs. It is noteworthy that, 1-MPSG significantly and selectively reduced...

Descripción completa

Detalles Bibliográficos
Autores principales: Komarnicka, Urszula K., Pucelik, Barbara, Wojtala, Daria, Lesiów, Monika K., Stochel, Grażyna, Kyzioł, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671550/
https://www.ncbi.nlm.nih.gov/pubmed/34907288
http://dx.doi.org/10.1038/s41598-021-03352-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671550/
https://www.ncbi.nlm.nih.gov/pubmed/34907288
http://dx.doi.org/10.1038/s41598-021-03352-2

Ejemplares similares