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CT‐guided microwave ablation in patients with lung metastases from breast cancer

BACKGROUND: Computed tomography (CT)‐guided percutaneous microwave ablation (MWA) is a very common ablation method that shows a good local tumor control rate in primary and secondary lung tumors. At present, few reports have explored the safety and efficacy of MWA for lung metastases from breast can...

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Autores principales: Meng, Min, Han, Xiaoying, Li, Wenhong, Huang, Guanghui, Ni, Yang, Wang, Jiao, Zhang, Tiehong, Dai, Jianjian, Zou, Zhigeng, Yang, Xia, Ye, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671896/
https://www.ncbi.nlm.nih.gov/pubmed/34725933
http://dx.doi.org/10.1111/1759-7714.14212
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author Meng, Min
Han, Xiaoying
Li, Wenhong
Huang, Guanghui
Ni, Yang
Wang, Jiao
Zhang, Tiehong
Dai, Jianjian
Zou, Zhigeng
Yang, Xia
Ye, Xin
author_facet Meng, Min
Han, Xiaoying
Li, Wenhong
Huang, Guanghui
Ni, Yang
Wang, Jiao
Zhang, Tiehong
Dai, Jianjian
Zou, Zhigeng
Yang, Xia
Ye, Xin
author_sort Meng, Min
collection PubMed
description BACKGROUND: Computed tomography (CT)‐guided percutaneous microwave ablation (MWA) is a very common ablation method that shows a good local tumor control rate in primary and secondary lung tumors. At present, few reports have explored the safety and efficacy of MWA for lung metastases from breast cancer. METHODS: From January 2012 to January 2018, 32 breast cancer patients with 46 pulmonary metastases received CT‐guided percutaneous MWA. The study was approved by the local institutional review board. The clinical efficacy and complications of MWA were investigated. RESULTS: The median follow‐up time was 32 months and the main effective rate was 97.8% (45/46). Five of 46 lesions had local progression (10.9%), with a median progression time of 10 months. The 1‐, 3‐, and 5‐year overall survival (OS) rates were 96.9%, 53.3%, and 17.8%, respectively. The median OS time was 36 months. Among 46 MWA treatments, 11 (23.9%) had massive pneumothorax, two (4.3%) had massive pleural effusion, and two (4.3%) had a pulmonary infection. CONCLUSION: CT‐guided percutaneous MWA may be safe and effective for treating lung metastases from breast cancer.
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spelling pubmed-86718962021-12-21 CT‐guided microwave ablation in patients with lung metastases from breast cancer Meng, Min Han, Xiaoying Li, Wenhong Huang, Guanghui Ni, Yang Wang, Jiao Zhang, Tiehong Dai, Jianjian Zou, Zhigeng Yang, Xia Ye, Xin Thorac Cancer Original Articles BACKGROUND: Computed tomography (CT)‐guided percutaneous microwave ablation (MWA) is a very common ablation method that shows a good local tumor control rate in primary and secondary lung tumors. At present, few reports have explored the safety and efficacy of MWA for lung metastases from breast cancer. METHODS: From January 2012 to January 2018, 32 breast cancer patients with 46 pulmonary metastases received CT‐guided percutaneous MWA. The study was approved by the local institutional review board. The clinical efficacy and complications of MWA were investigated. RESULTS: The median follow‐up time was 32 months and the main effective rate was 97.8% (45/46). Five of 46 lesions had local progression (10.9%), with a median progression time of 10 months. The 1‐, 3‐, and 5‐year overall survival (OS) rates were 96.9%, 53.3%, and 17.8%, respectively. The median OS time was 36 months. Among 46 MWA treatments, 11 (23.9%) had massive pneumothorax, two (4.3%) had massive pleural effusion, and two (4.3%) had a pulmonary infection. CONCLUSION: CT‐guided percutaneous MWA may be safe and effective for treating lung metastases from breast cancer. John Wiley & Sons Australia, Ltd 2021-11-02 2021-12 /pmc/articles/PMC8671896/ /pubmed/34725933 http://dx.doi.org/10.1111/1759-7714.14212 Text en © 2021 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Meng, Min
Han, Xiaoying
Li, Wenhong
Huang, Guanghui
Ni, Yang
Wang, Jiao
Zhang, Tiehong
Dai, Jianjian
Zou, Zhigeng
Yang, Xia
Ye, Xin
CT‐guided microwave ablation in patients with lung metastases from breast cancer
title CT‐guided microwave ablation in patients with lung metastases from breast cancer
title_full CT‐guided microwave ablation in patients with lung metastases from breast cancer
title_fullStr CT‐guided microwave ablation in patients with lung metastases from breast cancer
title_full_unstemmed CT‐guided microwave ablation in patients with lung metastases from breast cancer
title_short CT‐guided microwave ablation in patients with lung metastases from breast cancer
title_sort ct‐guided microwave ablation in patients with lung metastases from breast cancer
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671896/
https://www.ncbi.nlm.nih.gov/pubmed/34725933
http://dx.doi.org/10.1111/1759-7714.14212
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