ALG-2 and peflin regulate COPII targeting and secretion in response to calcium signaling

ER-to-Golgi transport is the first step in the constitutive secretory pathway, which, unlike regulated secretion, is believed to proceed nonstop independent of Ca(2+) flux. However, here we demonstrate that penta-EF hand (PEF) proteins ALG-2 and peflin constitute a hetero-bifunctional COPII regulato...

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Detalles Bibliográficos
Autores principales: Sargeant, John, Seiler, Danette Kowal, Costain, Tucker, Madreiter-Sokolowski, Corina T., Gordon, David E., Peden, Andrew A., Malli, Roland, Graier, Wolfgang F., Hay, Jesse C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671942/
https://www.ncbi.nlm.nih.gov/pubmed/34762908
http://dx.doi.org/10.1016/j.jbc.2021.101393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671942/
https://www.ncbi.nlm.nih.gov/pubmed/34762908
http://dx.doi.org/10.1016/j.jbc.2021.101393

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