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ALG-2 and peflin regulate COPII targeting and secretion in response to calcium signaling
ER-to-Golgi transport is the first step in the constitutive secretory pathway, which, unlike regulated secretion, is believed to proceed nonstop independent of Ca(2+) flux. However, here we demonstrate that penta-EF hand (PEF) proteins ALG-2 and peflin constitute a hetero-bifunctional COPII regulato...
Autores principales: | Sargeant, John, Seiler, Danette Kowal, Costain, Tucker, Madreiter-Sokolowski, Corina T., Gordon, David E., Peden, Andrew A., Malli, Roland, Graier, Wolfgang F., Hay, Jesse C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671942/ https://www.ncbi.nlm.nih.gov/pubmed/34762908 http://dx.doi.org/10.1016/j.jbc.2021.101393 |
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