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Ultrasound-Guided Microbubble-Mediated Locoregional Delivery of Multiple MicroRNAs Improves Chemotherapy in Hepatocellular Carcinoma

Rationale: To assess treatment effects of 4 complementary miRNAs (miRNA-100/miRNA-122/antimiRNA-10b/antimiRNA-21) encapsulated in a biodegradable PLGA-PEG nanoparticle, administered by an ultrasound-guided microbubble-mediated targeted delivery (UGMMTD) approach in mouse models of hepatocellular car...

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Detalles Bibliográficos
Autores principales: Wang, Huaijun, Hu, Zhongqian, Sukumar, Uday Kumar, Bose, Rajendran JC, Telichko, Arsenii, Dahl, Jeremy J, Paulmurugan, Ramasamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8671967/
https://www.ncbi.nlm.nih.gov/pubmed/34976581
http://dx.doi.org/10.7150/ntno.63320